Searchable abstracts of presentations at key conferences on calcified tissues

ba0004p56 | (1) | ICCBH2015

Abnormal functional responses of osteoblasts to leptin in adolescent idiopathic scoliosis

Tam Elisa Man Shan , Wang Zhiwei , Lee Wayne , Tang Shengping , Kar-Hing Yeung , Tsz-Ping Lam , Ng Bobby Kin Wah , Cheng Jack Chun Yiu

Objectives: Adolescent idiopathic scoliosis (AIS) is a complex three-dimensional structural deformity of the spine and its etiology remains unknown. Girls with AIS have taller stature, longer arm span, lower BMI, and generalized osteopenia. Leptin has been postulated as one of the etiologic factors of AIS because of its important physiological functions in neuro-osseous development affecting skeletal growth, bone metabolism, energy expenditure and body composition. Previous st...